Home > Growing tips & recipes > How to Identify and Manage Lettuce Big Vein Disease in Your Garden 6 min read 21.07.2025 How to Identify and Manage Lettuce Big Vein Disease in Your Garden Learn how to identify and manage Lettuce Big Vein Disease in your garden before it ruins your leafy harvests. Discover the tell-tale signs, how the disease spreads, and effective organic strategies for prevention and control. Protect your lettuce crop with these simple, natural steps. Lettuce is one of the stars of the early veg patch, quick to grow, endlessly useful, and the definition of garden-fresh. But when healthy plants suddenly develop pale, distorted leaves and refuse to head up properly, it can be a real blow. Lettuce Big Vein Disease may not be as well known as blight or mildew, but once it shows up, it can quickly put a stop to lush salad dreams.Let’s break down what this disease looks like, how it spreads, and what we can do to stop it in its tracks.What Is Lettuce Big Vein Disease?Lettuce Big Vein Disease is caused by a virus-like agent, but it’s actually carried and spread by a soil-borne fungus-like organism called Olpidium brassicae. This little pest lives in the soil and infects roots, allowing the virus to enter the plant.Symptoms typically appear in cool, damp conditions and include:Enlarged, translucent veins on older leaves (hence the name) Crinkled or twisted leaves Delayed heading or complete failure to form a proper lettuce head General loss of vigourIt doesn’t usually kill the plant outright, but it does make the lettuce completely unmarketable and frankly, unappetising.How Does It Spread?The tricky part is that Olpidium brassicae produces long-lived resting spores in the soil. These can sit dormant for years, waiting for just the right cool, moist conditions to reactivate and infect another round of lettuce roots. Once infected, there’s no cure, only prevention and smart management.Identifying Lettuce Big Vein EarlyEarly identification gives us a better chance to contain the damage. When growing lettuce, especially in spring or autumn when soil is damp and cool, keep an eye out for:Pale green to yellowing leaves with prominent veins Slower growth than usual Leaves that look slightly wrinkled or misshapen A failure to form dense heads, even after the usual harvest timeSymptoms often appear unevenly across a bed, as the spores aren’t evenly spread throughout the soil.How to Manage Lettuce Big Vein in the GardenOnce Big Vein shows up, it can linger in the soil for years, so it’s vital to take a long-term approach to managing the disease. Here’s what works:Rotate Crops ReligiouslyDon’t grow lettuce or other susceptible crops in the same soil for at least 3-4 years. Use that space for brassicas, carrots, or beans instead, crops that don’t host the pathogen.Avoid OverwateringSince the fungus thrives in damp conditions, watering should be done carefully, ideally early in the day to allow soil to dry out before nightfall. Raised beds and well-drained soil make a big difference.Remove Infected Plants PromptlyAny lettuce showing signs of Big Vein should be pulled and binned, not composted. This helps limit the spread of spores and reduces the chances of infecting nearby plants.Use Resistant VarietiesSome modern lettuce varieties have been bred to show resistance or tolerance to Big Vein. Look for resistant types when ordering seed especially if this disease has shown up in the garden before.Soil Solarisation (for the Determined)In very badly affected beds, solarisation is worth considering. This involves covering moist soil with clear plastic during the hottest weeks of summer to “cook” the top layer and kill off spores. It’s not a quick fix, but it can make a real difference over time.Lettuce Big Vein Disease might sound obscure, but for salad growers, it can be a real threat. By learning to spot the early signs and adjusting how and where we grow our lettuces, we can keep this soil-borne menace at bay. Healthy soil, healthy plants, and a bit of forward thinking, that’s the recipe for crisp, unblemished leaves all season long. Meet the author Nelly Nelly works in the She Grows Veg marketing department and is an incredible cook! She's learning how to grow veg fast in her very own container garden. Her favourites so far are the Dwarf Sunflower called 'Sunspot' and our Dwarf Pea called 'Tom Thumb'. Previous How to Prevent and Manage Mosaic Virus on Tomatoes, Cucumbers, and Beans Next How to Identify and Manage Potato Leaf Roll Virus for Healthier Yields